Abstract Background The antiproliferative effect of the Hsp90 inhibitor 17-AAG (17-allylamino-17-demethoxygeldanamycin) on human retinal pigment epithelial cells is investigated.Methods MTT and flow cytometry were used to study the antiproliferative effects of the 17-AAG treatment of Gate Hardware ARPE-19 cells.2D gel electrophoresis (2-DE) and mas
An analytical approach is presented to obtain the sloshing natural frequencies and modes of ideal liquid in a Lacrosse - Accessories rigid cylindrical container with a rigid annular baffle.The free surface waves of the liquid are considered in the analysis.The artificial interfaces are introduced to divide the complicated liquid domain into several
Rapid progress in developing multifunctional nanocarriers for drug delivery has been observed in recent years.Inorganic mesoporous silica nanocarriers (MSNs), emerged as an ideal candidate for Setting Powder gene/drug delivery with distinctive morphological features.These ordered carriers of porous nature have gained unique attention due to their d
Introduction The burden of multimorbidity is recognised increasingly in low- and middle-income countries (LMICs), creating a strong emphasis on the need for effective evidence-based interventions.Core outcome sets (COS) appropriate for the study of multimorbidity in LMICs do not presently exist.These are required to standardise reporting and contri